2010;11:32. Hines D: Poster #0742 March 2018 AADR. J Clin Dent. [16] in a systematic review in 2015. da Cruz LPD, Hill RG, Chen X, Gillam DG. 3. Martins C, Firmino R, Riva J, Ge L, Carrasco-Labra A, Brignardello-Petersen R, et al. The primary analysis population could be described as 32 participants per treatment group after lost to follow-ups of 12 out of 35 enrolled in the six-week trial who responded to the air blast stimulus for the primary outcome measure of treatment response one minute after topical application and after three days and two, four and six weeks subsequently, on SCASS with scores of2. 2008;29(8):1S-35S. We were using the PAS version.11, two independent sample t-test with 95% confidence interval and 80% power of test, meanSD of air blast stimulus test score of test group 1.860.41 and control group 2.220.41 two weeks after baseline test score, the calculated sample size was 22 [21] which was raised to 35 including five as drop out for each group (Fig. Pro-Argin Technology with arginine and an insoluble calcium compound, zinc and 1450ppm fluoride. Product Information. Post-application changes on SCASS were observed after one minute, three days, two, four, and six weeks, subsequently. 1997;24(11):80813. 1997;24(11):80813. Gently and effectively removes stains. Pessoa, Loretto et al. With regular use, it reduces teeth sensitivity and helps to strengthen gums and prevent gum recession. 4.4 5 0 198 198 Colgate Sensitive Pro-Relief Gum Therapy toothpaste helps instantly repair sensitive teeth and provides lasting protection against hypersensitivity. Follow the directions for use. A systematic review. 2018;2018:110. Table 5 presents the change in the mean scores of VAS against mechanical stimulus from baseline to subsequent efficacy interval within each treatment arm. The sensitive toothpaste works in different ways to fight cavities, remove plaque, promote gum health and freshen breath. All rights reserved. The formula consists of Arginine, an amino acid naturally found in saliva and also calcium from calcium carbonate. Explore the videos and articles found on this page to assist in better oral care. J Clin Dent. Benefits: Colgate Sensitive Prevent and Repair is clinically proven to provide superior relief vs Sensodyne Extra Whitening at 8 weeks1 Long-lasting relief from hypersensitivity with continued use Superior sensitivity relief at 8 weeks vs the leading Sensodyne toothpaste variant 1 Cite this article. 2015;42(2):13141. 2019;81:16. In each study, a single fingertip application of Colgate Sensitive Pro Relief was found to provide significant immediate relief relative to the comparative toothpaste, a result that was maintained over the subsequent three days with twice-daily brushing with the same toothpaste. Tel: +381 (0)21 452-910, +381 (0)21 420-758. Internal report 2018, 5. They reported more clinical efficacy with BioMin than Pro-argin reduction in air-blast stimulated DH on VAS after one month [39]. Pessoa OF, Loretto SC, Maia LC. 2009;22:3A-7A. Therefore, this trial was planned to investigate the clinical efficacy of Pro-argin and strontium acetate for immediate pain relief in DH after one minute of topical application to fill the research gap associated with limited published evidence and risk of bias in selection, performance, attrition, and reporting as predicted by Pessoa et al. Based on the synthesis of study results, we can conclude that Pro-argin in Colgate Sensitive Pro-relief and 8% strontium acetate in Sensodyne Rapid Action both are effective for pain relief in one minute after application in DH with better immediate treatment response of Pro-argin than strontium acetate. Significantly greater sensitivity reduction with twice - daily brushing compared to control toothpaste with potassium ions. IRB-1351/DUHS/Approval/2019/184. Many patients tolerate the pain of sensitive teeth because theyre unaware of simple but highly effective answers like Pro-Argin technology. This trial was registered in an ICMJE approved registry at https://clinicaltrials.gov/) under protocol Identifier: NCT04249336 [19] following the CONSORT guidelines [20] for parallel-group randomized trials after approval from the Institutional Review Board of Dow University of Health Sciences with reference no. A total of 140 participants were initially enrolled and randomised into the four treatment arms, with thirty-five in each group. Colgate Sensitive Pro Relief can be applied directly to the affected area for almost instant relief. Tandkrmen innehller zink fr att strka tandkttet och frhindra att tandkttet drar sig tillbaka, vilket r en av de vanligaste orsakerna till att . Post-hoc analysis revealed a significant reduction in DH scores in treatment arms compared to control on completing the six-week trial (p<0.05). Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. 2019;88:103170. Treatment difference between FCPS, Pro-argin, and 8% strontium acetate was not statistically significant with a p>0.05 for sustained pain relief in DH. 2009;20 (Spec Iss):123130. The clinical significance of this study can be highlighted by the fact that this was a person-centred clinical trial where patients were the prime focus where thepatients suffering from DH. J Dent Probl Solut. Results of our study, together with the results of the previous studies, confirm the immediate clinical efficacy of Pro-argin for the relief of DH. 2013;41(2):18794. 2019;46(12):11216. Grading of Recommendations, Assessment, Development and Evaluations. However, the manufacturers of the tested dentifrices were acknowledged in the study [34], so information bias wasexpected in the conducted trial. Matranga D, Matera F, Pizzo G. Evaluating the statistical methodology of randomized trials on dentin hypersensitivity management. Statistical Package for the Social Sciences software v.21.0. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. Dziki unikalnej formule Pro-Argin z arginin, wzmacnia szkliwo zbw i tym samym staj si one bardziej odporne na dziaanie kwasw. Cookies policy. Colgate Sensitive Pro-Relief Multi Protection Toothpaste provides clinically proven instant and lasting relief for sensitive teeth For instant relief, apply directly to each sensitive tooth with finger tip and gently massage for 1 minute, up to twice daily If symptoms persist, talk to your healthcare professional. Poster #0742, March 2018 AADR. Venkataramana S, Jeyaraman SK, Kothimbakkam SSK, Chellathurai BNK. SCASS and VAS were introduced on each visit as primary and secondary outcome measures, respectively. Pro-Argin technology can be found in Colgate Sensitive Pro Relief Toothpaste, sold as Colgate Sensitive Instant Relief in the UK and elmex Sensitive Professional in Europe. All participants were instructed to dry the tooth surface with the cotton ball and apply a paste of about half-inch length on the dried surface for one minute, then brush the teeth twice daily after breakfast and before sleep as per directions demonstratedon the study model. The next study outcome of our study wasrelated to 8% strontium acetate with clinical reduction of 37.6% on SCASS and 46% on VAS from baseline using mechanical and water jet stimuli immediately after topical application on sensitive teeth as depicted in Tables 3, 5, and 6. 2016;8:114. Colgate Sensitive Pro Relief was compared to a leading brand of desensitizing toothpaste containing stannous fluoride in a laboratory study, with confocal laser scanning microscopy and a novel imaging program used to qualify dentinal tubule occlusion. Am J Dent. Douglas-de-Oliveira DW, Vitor GP, Silveira JO, Martins CC, Costa FO, Cota LOM. Google Scholar. statement and Register now and gain access to: 8 hours ECPD Product samples Patient materials Register here * For instant relief, apply directly to the sensitive tooth with finger tip and gently massage for 1 minute. They explored greater tubular occlusion potential and more acid resistance of Pro-argin in comparison to FCPS after subsequent seven days of application on dentinal discs [38]. However, they also suggested further comparative evaluations of two dentifrices with large sample sizes as limited scientific evidence was found in previous studies [16]. Clinical Efficacy Of BioMin F, Colgate Sensitive Pro-Relief And Sensodyne Rapid Action Dentifrices In DH The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Canines and premolars are the most commonly affected teeth among 2530% of the adult population [2]. When you recommend Colgate Sensitive Pro Relief, you can help your dentin hypersensitivity patients to enjoy a pain-free life, confident in the knowledge that youre providing a highly effective, evidence-based solution. Colgate Sensitive Pro Relief Enamel Repair to strengthen weakened enamel and prevent enamel loss. Colgate* Sensitive Pro-Relief TM/MC Toothpaste with Pro-Argin TM/MC Technology is the first toothpaste that is clinically proven to provide instant & lasting relief from dentin hypersensitivity. 2017;9(4):e503. Moreover, the occluding potential of Pro-argin has also been ascertained in a previous in vitro analysis conducted by Lavender et al. Colgate Sensitive Pro Relief was found to achieve 91% dentin occlusion, compared to 67% for the stannous fluoride toothpaste. By using this website, you agree to our PubMed Mason S, Hughes N, Sufi F, Bannon L, Maggio B, North M, et al. Based on the outcomes of previous systematic reviews and meta-analysis, the rationale of the present study was to substantiate the claim of immediate pain relief after one-minute application in DH by non-invasive surface application of OTC dentifrices containing Pro-arginin Colgate Sensitive Pro-Relief, and 8% strontium acetate in Sensodyne Rapid Action and other objective was the comparative evaluation of the clinical efficacy of three technologies, BAG-based FCPS in BioMinR F, Pro-argin, and 8% strontium acetate at efficacy intervals of day three, week two, four and six for sustained inhibition of painful stimulus provoking DH as all three are dentinal tubular occluding dentifrices. volume21, Articlenumber:498 (2021) 1). The comparative evaluation was done for the clinical efficacy of Pro-argin and 8% strontium acetate, and a statistically significant (p>0.05) difference was not found between these two formulations in the current study. Dentine hypersensitivity. Colgate Sensitive Pro-Relief Enamel Repair contains Pro-Argin formula, helping to remineralise enamel, strengthen teeth against acid in food and drinks, plus instantly plugs channels to sensitive nerves. Lai et al. A meta-analysis by Yang et al. Buy Colgate Sensitive Pro Relief and get the best deals at the lowest prices on eBay! While 8% strontium acetate showed a greater clinical reduction in water jet stimulated DH on VAS than Pro-argin at all efficacy intervals, as demonstrated in Table 6. 4 Hines D et al. All rights reserved. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. The relief from sensitivity offered by Colgate Sensitive Pro Relief is proven to last. Arginine, Calcium Carbonate, Aqua, Sorbitol, Aroma, Poloxamer 407, Sodium Monofluorophosphate, Cocamidopropyl betaine, Zinc oxide, Benzyl Alcohol, Cellulose Gum, Zinc Citrate, Sodium Bicarbonate, Tetrasodium Pyrophosphate, Xantham Gum, Sodium Saccharin, Sucralose, Limonene, CL77891, 1. was used for statistical analysis. Therefore, it was considered to be rejected at a p valueof 0.05. It is clinically proven for instant and lasting Sensitivity relief* How does it work? Arshad, S., Zaidi, S.J.A. The participants with self-reported sensitivity in teeth were clinically diagnosed with DH. Get the best deals for COLGATE Sensitive Pro Relief Complete Protection Toothpaste 110g. For instant relief, just apply directly to the sensitive tooth with fingertip and gently massage for one minute. It is clinically proven for instant and lasting Sensitivity relief* How does it work? A randomised controlled, triple-blinded, phase-3 clinical trial was conducted at the Department of Periodontology at Dr Ishrat-ul-Ebad Khan Institute of Oral Health Sciences (DIKIOHS) in Dow University of Health Sciences (DUHS), Karachi, Pakistan from September 2019 to December 2020. Directions *For instant relief, apply directly to the sensitive tooth with fingertip, and massage gently for 60 seconds, one a week or less frequently **For lasting relief, apply to a gentle toothbrush making sure to brush all sensitive areas of the teeth. 2016;3(1):0504. For children 6-12 years of age, once a week or less frequently. Vu Pham T, Anh Nguyen T. Clinical evaluation of the desensitizing efficacy of a paste containing 8% arginine and calcium carbonate. 2009; 20 (Spec Iss): 1722. Plus it has the freshness you trust from Colgate! No adverse events like gingival inflammation, bad taste, allergies, fluoride incompatibility, and dental or tongue stains were observed for all dentifrices. This study investigated the relief from pain in DH in one minute after applying over the counter (OTC) dentifrices with Pro-Argin and strontium acetate and directly compared them with fluoro-calcium phospho-silicate (FCPS)-based dentifrices for immediate and sustained inhibition of painful stimulus provoking DH. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. If the enamel is too thin, has tiny tubules that reveal the underlying dentin, or is worn down in some places. Lasting relief with 2x daily continued brushing. Trials. In this way, variability in individuals' pain response was tried to be controlled and will be discussed in part 2 of this manuscript. 2017;30(4):2216. Builds a protective barrier that acts like . Colgate-Palmolive Company 2018. Dentin hypersensitivity treatments work in one of two ways. SA was the principal investigator and has contributed to design, data acquisition, analysis, and interpretation, and drafted the manuscript. This site is intended for healthcare professionals only. Published literature [16, 31, 43] has determined that all previous trials on treating DH were conducted on smaller samples, which might have prevented the results from being extrapolated on the general population. J Clin Dent 20 (2009), special issue 17-22, 3. However, we can conclude that both Pro-argin and strontium acetate-based dentifrices disrupt the pathophysiology of DH and are effective for immediate pain relief even one minute after application on sensitive teeth. SEALS & REPAIRS: Pro-Argin technology helps to seal and repair the sensitive areas of teeth. Lavender SA, Petrou I, Heu R, Stranick MA, Cummins D, Kilpatrick-Liverman L, et al. These outcomes were found in concordance with the previous controlled clinical trial conducted by Patel et al. Hu et al. PREVENTS SENSITIVITY COMING BACK: Sealed channels protect against pain for instant relief, and with regular use provide lasting protection to prevent sensitivity from . J Clin Dent 20 (2009), special issue 123-130, 2. 2020;20(3):101460. Google Scholar. Compend Contin Educ Dent. Gillam D, Hill R, Samueli A. Bioactive glasses in the management of dentine hypersensitivity: a review. How does Colgate Sensitive Pro-Relief Repair & Prevent work? If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. When it begins to interfere with oral hygiene, it can also lead to poor oral health outcomes. Individuals either with dental caries, heavily restored, or cracked teeth, or with orthodontic or prosthetic appliances, or with localised or generalised gingivitis or pulpitis and heavy calculus or using any desensitising toothpaste or mouth wash or any other desensitising products up to six weeks before the study were excluded from this trial. YYYY Colgate-Palmolive Company. It uses an 8% arginine and calcium carbonate formulation to quickly seal the open dentin tubules, replicating and enhancing the natural mechanism of hypersensitivity relief. Mahmoodi B, Wood R, Cook R. Protection and acid resistivity of bioactive-glasses, arginine and calcium silicate. 5 Hines D et al. Desensitizing toothpastes for dentin hypersensitivity: a network meta-analysis. It contains clinically proven Pro-Argin technology which provides instant and lasting sensitivity relief. who examined FCPS and Pro-argin formulations in 2018. Colgate Professional has resources to help your patients understand what causes enamel erosion and how to avoid falling into those traps. It revealed an immediate improvement with strontium acetate more than Pro-argin on SCASS. Today's era of flourishing research in DH is based on incorporating bioactive ingredients in commercially available oral dentifrices that can induce deep intratubular remineralisation of dental hard tissues for permanent or long-term treatment purposes. The second objective of the current study was to directly compare the clinical efficacy of FCPS, Pro-argin technology, and strontium acetate-based dentifrices due to their similar mode of action and tubular occluding potential in managing DH [36, 37]. Innehll Colgate Sensitive Instant Relief Enamel Repair r en fluortandkrm med Pro-Argin-teknologi som ger omedelbar smrtlindring vid ilningar i tnderna. For best performance, keep cap closed when not in use. The secondary objective of the study was to compare the clinical efficacy of Pro-argin, strontium acetate, and FCPS for immediate and sustained treatment response in DH that was measured on SCASS as a primary outcome measure and VAS as secondary outcome measure at efficacy intervals of one minute, day-three, week two, four and six. Learn more about caries in children from the resources provided on this page. However, Pro-argin formulation showed 8% more improvement in clinical symptoms of DH than strontium acetate formulation one minute after application. A previously published study by Samueli et al. Nathoo S, Delgado E, Zhang YP, DeVizio W, Cummins D, Mateo LR: Comparing the efficacy in providing instant relief of dentine hypersensitivity of a new toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride to a benchmark desensitizing toothpaste containing 2% potassium ion and 1450 ppm fluoride and to a control toothpaste with 1450 ppm fluoride: A three-day clinical study in New Jersey, USA. 2015;28(1):404. it is in a rubbish bin now. Fordeler Colgate SENSITIVE INSTANT Relief tannkrem er klinisk dokumentert virke i lpet av sekunder samtidig som den beskytter tannen mot at smerten skal komme tilbake. More robust trials with a large number of participants are recommended for furtherassessing the impact of DH on the oral health-related quality of life and the difference in the effectiveness of treatments. Dent Health Curr Res. [10] examined the evidence for strontium acetate and Pro-argin in 2018, and their findings depicted low quality of evidence for strontium acetate on the Grading of Recommendations, Assessment, Development, and Evaluations system (GRADE). 4.2 5 0 221 221 Colgate Sensitive Pro-Relief Enamel Rebuild toothpaste helps instantly repair sensitive teeth and provides lasting protection against hypersensitivity. fluorides, arginine, strontium, and bioactive glasses (BAG) [4] and in-office application of bioactive formulations such as glutaraldehyde, resin-based bonding agents and restorative materials, amorphous calcium phosphate based-tooth mousse, and lasers in the dental clinics [5]. Dentine Hypersensitivity. WHAT IS Colgate SENSITIVE INSTANT Relief Repair & Prevent? With its unique Pro-Argin technology, this sensitive toothpaste will give you instant* relief from sensitivity as it helps to seal and repair the sensitive areas of your teeth**. For more great Dental Care products like toothpaste and mouthwash, continue browsing online and buy in-store at B&M. Colgate Sensitive Instant Relief Toothpaste 75ml Product code: 326795 2.49 Subject to availability - visit your nearest store Soft tissues were isolated with cotton rolls, and adjacent teeth were isolated with cotton pellets. https://doi.org/10.1186/s12903-021-01864-x, DOI: https://doi.org/10.1186/s12903-021-01864-x. 2010;23(Spec No A):14A-9A. Ingredients *Calcium carbonate *Water The probable reason for variations between this clinical trial and previously conducted studies could be attributed to racial or ethnic differences between the conducted trials. Colgate Sensitive Pro Relief Instant Relief, Plugging the channels that lead to sensitive tooth nerves to help relieve sensitivity. In addition, one-Way ANOVA with Post Hoc Tukey for pair-wise comparison was used to compare treatment groups computing percent change from baseline with formula (post-application mean scores-baseline mean scores/baseline mean scores). Colgate Sensitive Pro-Relief Original Toothpaste This toothpaste gives you the freedom to forget about tooth sensitivity. and Ayad et al. Therefore, the first null hypothesis was that mean scores for pain due to DH among different treatment groups for immediate relief remain. J Non Cryst Solids. A total of 128 participants completed the trial. The Colgate Sensitive Pro Relief range features toothpastes that provide relief for sensitive teeth while addressing other common oral health concerns: Colgate Sensitive Pro Relief Repair and Prevent to protect against gingival recession. Network meta-analysis on the effect of desensitizing toothpastes on dentine hypersensitivity. A head-to-head comparative evaluation of these most effective bioactive agents, such as arginine and BAG-based desensitisers, was suggested by Martins et al. Colgate Sensitive Instant Relief Whitening Toothpaste 75 ml Pack of 5, Blocks Pain Instantly, Prevents Sensitivity, Gently Removes Stains (5 x 75 ml) 1,230 5 offers from 12.50 Colgate Sensitive Pro Relief Enamel Repair Toothpaste 75ml - 4 packs 94 22 offers from 14.14 Colgate Sensitive Instant Relief Enamel Repair Toothpaste 75 ml 190 Sriranganathan D, Chen X, Hing KA, Kanwal N, Hill RG. Not all desensitizing toothpastes perform equally well. Oral Care Products | Colgate Professional, Colgate Toothpaste - Dentists & Patients | Colgate Professional, Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste, Instantly* relieves dentine hypersensitivity, Long-lasting relief from the pain of sensitive teeth, Helps strengthen gums and prevent gum recession, Recommended fluoride level for caries protection (1450ppm). 2020;99(5):51422. 1):8A-15A. Colgate SENSITIVE INSTANT Relief Repair & Prevent toothpaste with PRO-ARGIN Technology and Zinc provides clinically proven instant* and lasting sensitivity relief1-2 plus lasting gum protection3. Dentin hypersensitivity is characterized by a short, sharp pain arising from open dentin tubules in exposed dentin in response to external stimuli, which cannot be attributed to any other defect or disease. Colgate Sensitive Instant* Relief Enamel Repair tandkrm ger dig kliniskt bevisad lngvarig lindring** mot ilningar i tta veckor nr du anvnder den tv gnger om dagen. Zinc helps strengthen gums and prevent gum recession a key cause of sensitivity1,2,3. 2 Docimo et al. J Oral Sci. observed a significantly greater reduction in sensitivity from air and tactile stimuli when compared to a potassium ion toothpaste, an effect sustained at two, four and eight weeks of use. These findings were similar to a previous study conducted by Schiff et al. Lg i kurv. 2017;71:18. A toothbrushing demonstration model from Nissin Company specification [PE-ORT002] was used to explain to the study participants about applying OTC dentifrices for one minute with the participant's finger. Ashwini S, Swatika K, Kamala DN. Ingredients *Calcium carbonate *Water For lsting relief, apply to a gentle toothbrush making sure to brush all sensitive areas of the teeth twice daily. 1. Participants were randomly allocated to four treatment arms and randomly assigned with OTC dentifrices having FCPS, Pro-argin, strontium acetate, and sodium fluoride (NaF) with an allocation ratio of 1:1:1:1. Click here. We provided oral hygiene instructions and ways of relieving their pain from DH to improve their quality of life. Colgate Sensitive Pro-Relief r en tandkrm som ger omedelbar och varaktig lindring mot ilningar i tnderna. 1,2 Participants were recalled at interim efficacy intervals of three days, two weeks, four weeks, and six weeks for assessment of sustained relief. A meta-analysis by Grnberg et al. Comparative efficacy of BioMin-F, Colgate Sensitive Pro-relief and Sensodyne Rapid Action in relieving dentin hypersensitivity: a randomized controlled trial, https://doi.org/10.1186/s12903-021-01864-x, https://clinicaltrials.gov/ct2/show/NCT04249336, http://creativecommons.org/licenses/by/4.0/, http://creativecommons.org/publicdomain/zero/1.0/. The dropouts of the participants at each efficacy interval may be considered the weakness of this trial that was due to COVID-19 lockdown. A meta-analysis by Matranga et al. 1). Kp nu. 2009;20(1):106. 1. (Table 1) (Fig. With the exclusive Pro-Argin formula, it provides instant* and lasting** relief by plugging the channels to block tooth sensitivity. Moreover, there was no significant difference between dentifrices containing FCPS, Pro-argin, and 8% strontium acetate (p>0.05) on completion of trial after six weeks. Directions for Use: For instant relief, apply directly to the sensitive tooth with finger tip and massage gently for 1 minute, up to twice a day and for children 6-12 years once a week or less frequently. Indian J Dent Sci. The price for Colgate Sensitive Pro-Relief is set at RM12.80 to avoid being categorized at RM13.00. These then interact to form a complex with positive charge. Participants were asked to pick up the envelope from the box. The datasets analysed during the current study are available from the corresponding author on reasonable request. This clinical trial was approved by the Institutional Review Board of Dow University of Health Sciences (Ref: IRB-1351/DUHS/Approval/2019/184) and was registered under the protocol ID NCT04249336 (https://clinicaltrials.gov/ct2/show/NCT04249336) on January 30, 2020, in accordance with the CONSORT statement of the updated guidelines for reporting randomised clinical trials. Yang ZY, Wang F, Lu K, Li YH, Zhou Z. Arginine-containing desensitizing toothpaste for the treatment of dentin hypersensitivity: a meta-analysis. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste with Pro-Argin Technology and Zinc. The Gum Health Physical is a new interactive digital tool you can use to quickly evaluate your patients in-office, and give them a personalized report they can use at home. The burden of dentine hypersensitivity. Clinically proven amino acid formula with Pro-Argin technology to provide sensitivity relief. Naturally, the researchers wondered whether it could help shield a person from acquiring the virus. FCPS was incorporated in OTC dentifrice with calcium, low contents of fluoride, and high contents of phosphate ions. The study's primary objective was to investigate pain relief in one minute after topical application of Pro-argin and strontium acetate on sensitive teeth in DH. The first post-treatment measure of SCASS and VAS scores was obtained immediately after removing dentifrices from teeth. This clinical trial was not funded by any agency in public, commercial or not-for-profit sectors. Provided by the Springer Nature SharedIt content-sharing initiative. In addition, patients were educated regarding the cause of the disease for prevention and awareness of oral hygiene measures, brushing techniques, and dietary influences in DH. Bae J-H, Kim Y-K, Myung S-K. Desensitizing toothpaste versus placebo for dentin hypersensitivity: a systematic review and meta-analysis. The treatment difference between Pro-argin and 8% strontium acetate was not statistically significant with a p>0.05 for immediate and sustained pain relief in DH and statistically significant relative to control on all clinical parameters of the SCASS and VAS. J Clin Exp Dent. Comparative efficacy of BioMin-F, Colgate Sensitive Pro-relief and Sensodyne Rapid Action in relieving dentin hypersensitivity: a randomized controlled trial.
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